Preferential and cooperative binding of histone I to chromosomal mammalian DNA.
نویسنده
چکیده
There is a strong preferential binding of histone I to lymphocyte DNA as compared to Escherichia coli DNA when large DNA fragments (2 times 10-6 daltons) are used. The binding of histone I to lymphocyte DNA and to E. coli DNA is cooperative. The distribution of preferential binding sites has been investigated on fragmented DNA. Most of the 2 times 10-6 dalton fragments were found to have at least one preferential histone I binding site, whereas most of the 2 times 10-5 dalton fragments have none.
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عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 72 2 شماره
صفحات -
تاریخ انتشار 1975